Chronic Inflammatory Response Syndrome (CIRS) a Comprehensive OverviewChronic Inflammatory Response Syndrome (CIRS) is a complex and debilitating condition that affects countless individuals, often leaving them struggling to find effective treatment and relief.

Dr. Andrea Jordheim, a leading Upper Cervical Chiropractor and CIRS Provider at Transformation Wellness Center in Grand Junction, CO, is dedicated to helping patients navigate the challenges of CIRS through the implementation and utilization of the peer-reviewed and data-driven, Shoemaker Protocol. In this comprehensive blog post, we will delve into the intricacies of CIRS, its symptoms, causes, and the revolutionary Shoemaker Protocol that offers hope for those suffering from this condition.

Understanding Chronic Inflammatory Response Syndrome (CIRS)

What is CIRS?

Chronic Inflammatory Response Syndrome (CIRS) is a multi-system, multi-symptom illness triggered by exposure to biotoxins. These biotoxins are harmful substances produced by certain molds, bacteria, fungi, and other microorganisms. When a susceptible individual is exposed to these biotoxins, their immune system can become dysregulated, leading to chronic inflammation and a wide array of debilitating symptoms.

Causes of CIRS

CIRS can be caused by exposure to various environmental factors, including:

  1. Mold: Exposure to toxic mold, commonly found in water-damaged buildings, is one of the primary causes of CIRS.
  2. Tick Bite: Infections caused by tick-borne pathogens can trigger a chronic inflammatory response.
  3. Harmful Algal Blooms (HABs): Toxins produced by certain types of algae can cause CIRS.
  4. Bacteria: Exposure to Actinomycetes bacteria and other bacterial endotoxins can also lead to CIRS.

Symptoms of CIRS

CIRS can manifest in a wide range of symptoms that affect multiple systems of the body. Common symptoms include:

  • Chronic fatigue and weakness
  • Muscle and joint pain
  • Headaches and migraines
  • Cognitive difficulties (often referred to as “brain fog”)
  • Shortness of breath
  • Sinus congestion and respiratory issues
  • Gastrointestinal problems
  • Visual disturbances
  • Mood disorders such as anxiety and depression
  • Numbness or tingling sensations

Diagnosis of CIRS

Diagnosing CIRS can be challenging due to the complexity and variety of symptoms. A thorough evaluation by a healthcare professional experienced in CIRS is essential. The diagnosis typically involves:

  1. Medical History: A detailed medical history, including exposure to potential biotoxins and previous health issues.
  2. Physical Examination: A comprehensive physical examination to assess symptoms and rule out other conditions.
  1. Genetic Testing: Testing for specific genetic markers (HLA-DR) that can indicate a predisposition to developing CIRS.3. 
  2. Laboratory Tests: Specific blood tests to measure markers of inflammation and immune system dysregulation, such as C4a, MMP-9, and TGF-beta1. Brain and neuroregulatory hormones including, MSH, ADH, ACTH, VIP, and other blood markers such as VEGF, Androgens, gluten sensitivity markers, leptin, etc.
  3. Visual Contrast Sensitivity (VCS) Test: A non-invasive test that can help identify deficits in the ability to distinguish contrast, which is often impaired in CIRS patients.

The Shoemaker Protocol

The Shoemaker Protocol, developed by Dr. Ritchie Shoemaker, is a comprehensive treatment plan designed to address the underlying causes of CIRS and alleviate its symptoms. This protocol involves multiple steps, each targeting a different aspect of the condition.

Step 1: Remove Exposure to Biotoxins

The first and most crucial step in the Shoemaker Protocol is to eliminate exposure to the source of biotoxins. This may involve:

  • Remediating mold-infested buildings or finding a new living environment free from mold.
  • Treating chronic infections such as Lyme disease or sinus infections.
  • Avoiding areas affected by harmful algal blooms.

Step 2: Binding Toxins

Once exposure to biotoxins has been eliminated, the next step is to remove the toxins from the body. This is typically done using bile acid sequestrants such as cholestyramine or Welchol. These medications bind to biotoxins in the gastrointestinal tract and help excrete them from the body.

Step 3: Correcting Dysregulated Inflammation

CIRS is characterized by chronic inflammation. The Shoemaker Protocol includes steps to reduce inflammation and correct immune system dysregulation:

  • VIP (Vasoactive Intestinal Peptide): A nasal spray that can help reduce inflammation and improve various symptoms of CIRS.
  • Omega-3 Fatty Acids: Supplementation with high-quality fish oil to reduce inflammation.
  • Antioxidants: Supplements such as glutathione and alpha-lipoic acid to combat oxidative stress.

Step 4: Addressing Hormonal Imbalances

CIRS can disrupt the endocrine system, leading to hormonal imbalances. The Shoemaker Protocol includes measures to correct these imbalances:

  • Adrenal Support: Supplements and lifestyle changes to support adrenal gland function.
  • Thyroid Hormone Replacement: If necessary, to correct hypothyroidism.
  • Sex Hormone Balance: Addressing imbalances in estrogen, progesterone, and testosterone.

Step 5: Improving Immune Function

Supporting the immune system is a critical aspect of the Shoemaker Protocol. This involves:

  • Low-Dose Naltrexone (LDN): A medication that can help modulate the immune system.
  • Probiotics and Prebiotics: To support gut health and overall immune function.
  • Vitamin D: Supplementation to support immune health.

Step 6: Additional Support and Maintenance

The final step often modified per patient need is not part of the core Shoemaker Protocol, however, it supports maintenance and aims to prevent relapse and ensure long-term health:

  • Lifestyle Recommendation: To address ongoing health and vitaility.
  • Nutritional Support: A balanced diet rich in anti-inflammatory foods.
  • Stress Management: Techniques such as mindfulness, meditation, and yoga to reduce stress and support overall well-being.

Upper Cervical Chiropractic Care and CIRS

Upper Cervical Chiropractic care can play a valuable role in the management of CIRS, complementing the Shoemaker Protocol by addressing musculoskeletal issues and promoting overall wellness. Dr. Andrea Jordheim at Transformation Wellness Center offers specialized upper chiropractic care to support CIRS patients.

Benefits of Chiropractic Care for CIRS

  1. Pain Relief: Chiropractic adjustments can help alleviate muscle and joint pain commonly experienced by CIRS patients.
  2. Improved Mobility: Restoring proper alignment and function to the spine and joints can improve mobility and reduce stiffness.
  3. Enhanced Nervous System Function: Chiropractic care can support nervous system health, potentially improving symptoms like brain fog and cognitive difficulties.
  4. Stress Reduction: Chiropractic treatments can promote relaxation and reduce stress, which is beneficial for overall health and well-being.

Chiropractic Techniques for CIRS

Dr. Andrea Jordheim utilizes a variety of chiropractic techniques tailored to the needs of CIRS patients:

  • Gentle Adjustments: Low force, spring-loaded instrument adjustments improve spinal mobility and function with is often necessary for patients with CIRS.
  • Soft Tissue Therapy: Treatments such as therapeutic soft tissue work help address muscle tension and pain.
  • Rehabilitation Exercises: Personalized exercise programs to strengthen muscles, improve stability, and support overall health.

Living with CIRS: Tips for Patients

Living with CIRS can be challenging, but there are several strategies that can help manage symptoms and improve quality of life:

  1. Create a Safe Environment: Ensure that you’re living and working environments are free from mold and other biotoxins.
  2. Follow the Shoemaker Protocol: Adhere to the treatment plan prescribed by your healthcare provider.
  3. Stay Hydrated: Drink plenty of water to support detoxification and overall health.
  4. Eat a Nutritious Diet: Focus on anti-inflammatory foods, such as fruits, vegetables, lean proteins, and healthy fats.
  5. Exercise Regularly: Engage in gentle, regular physical activity to support overall health and well-being.
  6. Practice Stress Management: Incorporate stress-reducing activities such as meditation, deep breathing exercises, and yoga into your daily routine.
  7. Get Adequate Sleep: Prioritize good sleep hygiene and aim for 7-9 hours of sleep per night to support your body’s healing processes.
  8. Stay Informed: Educate yourself about CIRS and stay informed about new treatments and strategies for managing the condition. CIRSx.com and Survivingmold.com are wonderful websites that go into dept on CIRS and published research/conferences.
  9. 8. Connect with Others: CIRS can be an isolating illness. It is important to surround yourself with support from understanding individuals. Patients often find tremendous value in joining support groups like the “CIRS Healing Collective”.

Frequently Asked Questions (FAQs)

What is the Shoemaker Protocol?

The Shoemaker Protocol is a comprehensive treatment plan developed by Dr. Ritchie Shoemaker to address the underlying causes of Chronic Inflammatory Response Syndrome (CIRS). It involves multiple steps, including removing exposure to biotoxins, binding toxins, reducing inflammation, correcting hormonal imbalances, and supporting immune function.

How is CIRS diagnosed?

CIRS is diagnosed through a combination of medical history, physical examination, laboratory tests (such as measuring inflammatory markers and genetic testing), and the Visual Contrast Sensitivity (VCS) test.

Can upper cervical chiropractic care help with CIRS?

Yes, upper cervical chiropractic care can complement the Shoemaker Protocol by addressing nervous system imbalance, musculoskeletal issues, providing pain relief, improving mobility, enhancing nervous system function, and reducing stress.

What are the common symptoms of CIRS?

Common symptoms of CIRS include chronic fatigue, muscle and joint pain, headaches, cognitive difficulties, shortness of breath, dizziness, weight gain, sinus congestion, gastrointestinal problems, visual disturbances, mood disorders, and numbness or tingling sensations.

How long does it take to see improvements with the Shoemaker Protocol?

The timeline for seeing improvements with the Shoemaker Protocol can vary depending on patient exposures, the chronicity and severity of their condition and the individual’s response to treatment. Some patients may notice improvements within a few weeks, while others may take several months.

CIRS—there is hope!

Chronic Inflammatory Response Syndrome (CIRS) is a complex and challenging condition, but with the right approach and treatment, patients can find significant relief and improve their quality of life. The Shoemaker Protocol offers a comprehensive, evidence-based treatment for Chronic Inflammatory Response Syndrome (CIRS).

If you or a loved one is struggling with CIRS, consider reaching out to Dr. Andrea Jordheim for a thorough evaluation and personalized treatment plan. We are here to help you navigate the complexities of CIRS and support you on your journey to better health.

Contact Information:

  • Address: 2501 Blichmann Avenue, Suite 110, Grand Junction, CO 81505
  • Email: Info@mytransformationwellness.com
  • Phone: (970) 812-5559

Take the first step towards healing and managing Chronic Inflammatory Response Syndrome by scheduling an appointment with Dr. Andrea Jordheim today. Together, we can work towards restoring your health and improving your quality of life through comprehensive and compassionate care.

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